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Kratom (Mitragyna speciosa) offers a unique interaction with the body’s mu opioid receptor (MOR), distinguishing it from classical opioids like morphine. When opioids bind to the MOR, they typically activate G proteins, which provide pain relief, and beta arrestin 2, a protein linked to tolerance, desensitization, and dangerous side effects like respiratory depression, which can lead to overdose.
Kratom 19-10-2024
Opiates such as Tramadol, Oxycodone, Hydrocodone, and Codeine are on the rise in New Zealand. While short-term use of these medications can be beneficial, dependence can develop rapidly leading to severe complications.
Kratom 30-04-2024
Arthritis is a term used for more than 140 conditions that affect the joints. Pain and stiffness are the most common symptoms.
CBD Oil 07-02-2024
A kratom potentiator, in the most general sense, is a substance which can be taken to increase the effect kratom has on an individual. This is important as the aim should always be to take the optimal therapeutic dose in order to maximize benefits and minimize side effects.
Kratom 03-02-2024